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--- title: "NACC" type: concept related: [Nacc] source: https://www.jemoka.com/posts/kbhnacc/ confidence: high status: active --- NACC is a large, longitudinal dataset for neurodegentitive disease as a project in collaboration with Dr. Alyssa Weakley at UC Davis. Dr. Alyssa Weakley is interested in Early Cognitive Change Mild Cognitive Impairment (MCI) “How early can we detect, using NACC, change?” dataset construction Participants are given a battery of mental capacity tests, these values are tracked over time There are also family member questionnaire Neuroimaging and biomarker data Other things tracked in the data— Amyloid levels of spinal fluid Detecting even earlier focus good to focus on specifically alzheimer’s type dementia (so, ignore things on lewy body disease) Using clinical diagnosis as the dependent variable, but good to see the autopsy results Items 3 and 7 are independent codes; if alzhimer’s is measured, MCI is not measured. visa versa.